What is Colloidal Gold Used For?

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Gold is a high-quality hedge hedging tool, favored by investors. Especially in recent years, with the increasing instability of the world economy, gold has become one of the preferred asset allocations of investors because of its functions of hedging and fighting inflation. 

Earlier, the worsening situation in Ukraine sent gold prices soaring to a two-year high of $2,070 an ounce. But gold, along with other commodities, fell back last week as conditions changed and bulls took profits, hitting a low of $1,895 an ounce. Rising gold prices may also have an impact on the colloidal gold prices. 

According to China Business News, Goldman Sachs raised its gold price forecast in early March, considering Asian buyers' gold consumption demand, investment demand and central bank gold purchase demand continue to rise. Three -, six - and 12-month targets were raised to $2,300, $2,500 and $2,500 an ounce, respectively, from $1,950, $2,050 and $2,150. The last time all three accelerated was in 2010-11 when gold prices rose nearly 70%. 

The World Gold Council has also noted that global gold demand is at its highest level in nearly two years, which is linked to a recovery in consumption and consumer sentiment to combat inflation. 

Tumor detection 
In cancer research, colloidal gold can be used to target tumors and detected in vivo using SERS (Surface-enhanced Raman spectroscopy). Surrounded by Raman reporter molecules, the gold nanoparticles emit light 200 times brighter than quanta. It found that Raman molecules were stabilized when nanoparticles were coated with a mercaptan modified polyethylene glycol coating. This allows compatibility and circulation in the body.  To specifically target tumor cells, pegylated gold particles are conjugated with antibody (or antibody) fragments, such as scFv, that target, for example, the epidermal growth factor receptor, which is sometimes overexpressed in cells of certain cancer types. Using SERS, these pegylated gold nanoparticles were able to detect tumor locations. 
Gold nanoparticles accumulate in tumors due to leakage of tumor vasculature and can be used as contrast agents to enhance imaging in time-resolved optical tomography systems using short pulsed lasers for skin cancer detection in mouse models. The spherical gold nanoparticles applied widened the time distribution of the reflected light signal and enhanced the contrast between the surrounding normal tissue and the tumor. 
 
Chemotherapy 
Gold nanoparticles in chemotherapy and radiation therapy are colloidal gold used in therapy, usually for cancer or arthritis. Gold nanoparticles show promise in advances in cancer treatment. Some properties of gold nanoparticles, such as their small size, non-toxicity and non-immunogenicity, make these molecules useful candidates for targeted drug delivery systems. Using tumor-targeted delivery vectors becomes smaller and the ability to bypass the body's natural barriers and obstacles becomes more possible. To increase the specificity and likelihood of drug delivery, tumor-specific ligands can be transplanted to particles along with chemotherapeutic drug molecules to allow these molecules to circulate throughout the tumor without redistributing into the body.
 
Gene therapy 
Gold nanoparticles have shown potential as intracellular delivery vectors for siRNA oligonucleotides with the greatest therapeutic impact. 
Gold nanoparticles have shown potential as intracellular delivery vectors for antisense oligonucleotides (single- and double-stranded DNA) by providing protection against intracellular nucleases and easily targeted functionalization. 
 
Biosensor
Gold nanoparticles are incorporated into biosensors to enhance their stability, sensitivity and selectivity. Nanoparticle properties such as small size, high surface volume ratio and high surface energy can immobilize a wide range of biomolecules. In particular, gold nanoparticles can act as "electron wires" to transmit electrons, amplifying electromagnetic light so that they can act as signal amplifiers. The main types of biosensors based on gold nanoparticles are optical and electrochemical biosensors.
 
Colloidal Gold Price
The price is influenced by many factors including the supply and demand in the market, industry trends, economic activity, market sentiment, and unexpected events.
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Europe has been facing the gas shortage problem since the second half of 2021. The worsening situation in Russia and Ukraine has reduced Russian gas shipments to Europe, leading to a doubling of European gas prices. Energy shortages have sent electricity prices soaring. For these reasons, it is predicted that the price of the colloidal gold will continue to increase.

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